CaMKII - from Bench to Bedside

DRA symposium

The protein family of calcium/calmodulin-dependent protein kinase II (CaMKII), particularly the variant CaMKIIa, is highly expressed in the mammalian brain, and is critically important for synaptic plasticity underlying learning and memory. Furthermore, dysregulated signalling occurs in several neurological disorders making CaMKII’s relevant, yet underexplored, drug targets. This symposium will cover fundamental aspects of CaMKII signalling, and its role in health and disease.

Programme

14:00 - 14:05 Welcome
Prof. Petrine Wellendorph, Department of Drug Design and Pharmacology, University of Copenhagen, Denmark
14:05 - 14:35

Postsynaptic CaMKIIa as an autoregulated scaffolding protein
Prof. Roger Colbran, Molecular Physiology and Biophysics, Vanderbilt University, USA
14:35 - 15:05

The role of CaMKIIa autophosphorylation at T286 in synaptic plasticity and memory formation
Prof. Karl Peter Giese, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK
15:05 - 15:25

Coffee break
15:25 - 15:55

Role of CAMK2 in neurodevelopment disorders
Assoc. Prof. Geeske van Woerden, Department of Neuroscience, ERASMUS MC, The Netherlands
15:55 - 16:00

Wrap-up by Petrine Wellendorph

The symposium is organized on behalf of the graduate programme in pharmaceutical sciences, Drug Research Academy, by Prof. Petrine Wellendorph, Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen.

The symposium is free of charge and open for attendance by all interested parties. It is not necessary to pre-register.